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Anti-CD46 Antibody(monoclonal, 9E9)

AHUS2 antibody|Antigen defined by monoclonal antibody| TRA 2 10 antibody|Antigen identified by monoclonal antibody| TRA 2 10 antibody|CD46 antibody|CD46 antigen antibody|CD46 antigen complement regulatory protein antibody|CD46 molecule antibody|CD46 molecule complement regulatory protein antibody|Complement membrane cofactor protein antibody|MCP antibody| MCP_HUMAN antibody|Measles virus receptor antibody|membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen) antibody|Me

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一抗 - 单克隆抗体

说明书:

M00377-Dyl488

1980元/100ul  

human

FCM

Monoclonal(Clone: 9E9)

现货

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Product Brief

  • 产品概况

    货号 M00377-Dyl488
    产品名称 Anti-CD46 Antibody(monoclonal, 9E9)
    基因名 CD46
    抗体来源 Mouse
    克隆 Monoclonal(Clone: 9E9)
    抗体亚型 Mouse IgG1
    免疫原 A synthetic peptide corresponding to a sequence at the C-terminus of human CD46 (366-392aa YRYLQRRKKKGTYLTDETHREVKFTSL).
    内容 500ug/ml antibody with PBS ,0.02% NaN3 , 1mg BSA
    纯化方式 protein G purified.
    浓度 500ug/ml
    产品形态 Liquid
    保存条件 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing.
    背景资料 CD46 complement regulatory protein also known as CD46 (cluster of differentiation 46) and Membrane Cofactor Protein is a protein which in humans is encoded by the CD46 gene. The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. And the encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.
    研究类别 1. "Entrez Gene: CD46 CD46 molecule, complement regulatory protein".2. Liszewski MK, Post TW, Atkinson JP (1991). "Membrane cofactor protein (MCP or CD46): newest member of the regulators of complement activation gene cluster".Annu. Rev. Immunol. 9 (1): 431–55.3. Taylor CT, Biljan MM, Kingsland CR, Johnson PM (May 1994). "Inhibition of human spermatozoon-oocyte interaction in vitro by monoclonal antibodies to CD46 (membrane cofactor protein)". Hum. Reprod.9 (5): 907–11.
    Uniprot ID CD46: P15529
    推荐配套的二抗和检测试剂 Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0001-1) for IHC(P). *Blocking peptide 可以联系我们购买。

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