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Anti-RP2 Antibody (monoclonal, 3D7)

Protein XRP2; RP2

分类:

一抗 - 单克隆抗体

说明书:

M01923

860元/50ul  1520元/100ul  2280元/150ul  

human, mouse, rat

WB,FCM

Monoclonal

现货

总价格:

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选择数量:

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Product Brief

  • 产品概况

    货号 M01923
    产品名称 Anti-RP2 Antibody (monoclonal, 3D7)
    基因名 RP2
    抗体来源 Mouse
    克隆 Monoclonal
    抗体亚型 Mouse IgG2b
    免疫原 E. coli-derived human RP2?recombinant protein (Position: D244-M348).
    内容 Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
    纯化方式 Immunogen affinity purified.
    产品形态 Lyophilized
    保存条件 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing.
    背景资料 Protein XRP2?is a?protein?that in humans is encoded by the?RP2?gene. It is mapped to Xp11.3. The RP2 locus has been implicated as one cause of X-linked retinitis pigmentosa. The predicted gene product shows homology with human cofactor C, a protein involved in the ultimate step of beta-tubulin folding. Progressive retinal degeneration may therefore be due to the accumulation of incorrectly folded photoreceptor or neuron-specific tubulin isoforms followed by progressive cell death.?The RP2 protein is also involved in regulating the function and extension of outer segment of cone photoreceptors in mice.
    研究类别 1. Chapple, J. P., Hardcastle, A. J., Grayson, C., Spackman, L. A., Willison, K. R., Cheetham, M. E.Mutations in the N-terminus of the X-linked retinitis pigmentosa protein?RP2?interfere with the normal targeting of the protein to the plasma membrane.?Hum. Molec. Genet. 9: 1919-1926, 2000.2. Evans, R. J., Schwarz, N., Nagel-Wolfrum, K., Wolfrum, U., Hardcastle, A. J., Cheetham, M. E.The retinitis pigmentosa protein?RP2links pericentriolar vesicle transport between the Golgi and the primary cilium.?Hum. Molec. Genet. 19: 1358-1367, 2010.?
    Uniprot ID RP2: O75695
    推荐配套的二抗和检测试剂 Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0001-1) for IHC(P). *Blocking peptide 可以联系我们购买。

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