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Anti-IDH1 Antibody (monoclonal,16H7)

Cytosolic NADP isocitrate dehydrogenase antibody|Cytosolic NADP-isocitrate dehydrogenase antibody|Epididymis luminal protein 216 antibody|Epididymis secretory protein Li 26 antibody|HEL-216 antibody|HEL-S-26 antibody|ICDH antibody|IDCD antibody|IDH antibody|IDH1 antibody|IDHC_HUMAN antibody|IDP antibody|IDPC antibody|Isocitrate dehydrogenase [NADP] cytoplasmic antibody|Isocitrate dehydrogenase 1 (NADP+) soluble antibody|NADP dependent isocitrate dehydrogenase cytosolic antibody|NADP dependent is

分类:

一抗 - 单克隆抗体

说明书:

M00129-1

860元/50ul  1520元/100ul  2280元/150ul  

human,mouse,rat

WB,ICC/IF,FCM

Monoclonal

现货

总价格:

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Product Brief

  • 产品概况

    货号 M00129-1
    产品名称 Anti-IDH1 Antibody (monoclonal,16H7)
    基因名 IDH1
    抗体来源 Mouse
    克隆 Monoclonal
    抗体亚型 Mouse IgG1
    免疫原 A synthetic peptide corresponding to a sequence at the C-terminus of human IDH1 (381-413aa KGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAK),different from the related mouse and rat sequences by one amino acid.
    内容 Each vial contains 4mg Trehalose,0.9mg NaCl,0.2mg Na2HPO4,0.05mg NaN3.
    纯化方式 Immunogen affinity purified.
    产品形态 Lyophilized
    保存条件 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing.
    背景资料 Isocitrate dehydrogenase 1 (NADP+),soluble is an enzyme that in humans is encoded by the IDH1 gene. Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses,one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases,which localize to the mitochondrial matrix,and two NADP(+)-dependent isocitrate dehydrogenases,one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. It contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions,such as the conversion of 2,4-dienoyl-CoAs to 3-enoyl-CoAs,as well as in peroxisomal reactions that consume 2-oxoglutarate,namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
    Uniprot ID IDH1: O75874
    推荐配套的二抗和检测试剂 Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0001-1) for IHC(P). *Blocking peptide 可以联系我们购买。

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